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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC6A6
All Species:
28.18
Human Site:
Y489
Identified Species:
62
UniProt:
P31641
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31641
NP_001127839.1
620
69830
Y489
I
Y
G
G
D
N
L
Y
D
G
I
E
D
M
I
Chimpanzee
Pan troglodytes
XP_001157641
620
69651
Y489
I
Y
G
G
D
N
L
Y
D
G
I
E
D
M
I
Rhesus Macaque
Macaca mulatta
Q9MYX0
630
70239
E493
A
Y
V
V
K
L
L
E
E
Y
A
T
G
P
A
Dog
Lupus familis
XP_533741
630
70351
Y495
V
Y
G
S
N
R
F
Y
D
N
I
E
D
M
I
Cat
Felis silvestris
Mouse
Mus musculus
O35316
621
69837
Y489
I
Y
G
G
D
N
L
Y
D
G
I
E
D
M
I
Rat
Rattus norvegicus
P31643
621
69850
Y489
I
Y
G
G
D
N
L
Y
D
G
I
E
D
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521283
733
81919
Y602
V
Y
G
A
D
N
F
Y
D
A
I
E
D
M
I
Chicken
Gallus gallus
NP_001025771
631
71046
Y489
V
Y
G
A
D
N
I
Y
D
A
I
E
D
M
I
Frog
Xenopus laevis
A7Y2X0
790
87434
C655
I
Y
G
L
Q
R
F
C
E
D
I
E
M
M
I
Zebra Danio
Brachydanio rerio
NP_001032750
625
69879
Y489
V
Y
G
A
D
N
F
Y
D
A
I
E
E
M
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VR07
943
103618
K782
Y
G
T
G
R
L
S
K
N
V
K
Q
M
T
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
42.7
58.4
N.A.
93.2
93.7
N.A.
71.2
79.4
34.8
78.5
N.A.
29.1
N.A.
N.A.
N.A.
Protein Similarity:
100
98.3
60.9
72
N.A.
97.4
97.7
N.A.
78.5
88.1
51.9
88.1
N.A.
42.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
60
N.A.
100
100
N.A.
73.3
73.3
46.6
66.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
73.3
N.A.
100
100
N.A.
80
86.6
53.3
80
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
28
0
0
0
0
0
28
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
64
0
0
0
73
10
0
0
64
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
19
0
0
82
10
0
0
% E
% Phe:
0
0
0
0
0
0
37
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
82
46
0
0
0
0
0
37
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
46
0
0
0
0
0
10
0
0
0
82
0
0
0
82
% I
% Lys:
0
0
0
0
10
0
0
10
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
10
0
19
46
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
19
82
0
% M
% Asn:
0
0
0
0
10
64
0
0
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
10
19
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
10
0
10
0
% T
% Val:
37
0
10
10
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
91
0
0
0
0
0
73
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _